For researchers · PULSE on the US PRO 2000

Programmable
ultrasound,
in one hand.

PULSE turns the US PRO 2000, a handheld 1 MHz ultrasound, into an instrument you program from a phone. Pick a pulse program from a signed library, load it in seconds over NFC, and run timed sessions at three intensities. For a study, we build the program with you.

Inquire about a research package →See the hardware

RESEARCH & DEVELOPMENT USE ONLY · NOT A MEDICAL DEVICE · SHIPS WITHIN THE US

The US PRO 2000 with a clear front cover, showing the PULSE board installed under the front panel

3D · FROM SCAN + CAD

01 · THE SYSTEM

Four parts, one loop.

A program goes from your account to the phone, over NFC into PULSE, and PULSE programs the ultrasound. Here is each part, in the order a program travels.

The UltraNFC app's Library on an iPhone — 01 · LIBRARY
Signed pulse programs.
39 programs in the library today. Each is a firmware image signed by UltraDAO and checked on the device before it runs.

The top edge of an iPhone touching the POWER switch on the US PRO 2000 — 02 · ULTRANFC APP
Load it from a phone.
The UltraNFC app for iPhone and Android holds your library. Hold the phone to the POWER switch and the program goes over NFC; the app reads it back to confirm.

The PULSE board taken apart: its NFC chip, flash and RP2040 lifted off the board — 03 · PULSE MODULE
The board inside.
Under the front panel: a PN7150 NFC front end, W25Q64 flash and an RP2040 that programs the instrument. Six spring pins connect it; nothing is soldered.

The US PRO 2000's front panel with the POWER, H and 10-minute lights on — 04 · US PRO 2000
The instrument.
A Ø24 mm piezo transducer at 1 MHz, 0.08–1.6 W/cm² in steps, about 40 mm effective depth in soft tissue. MODE sets the intensity, TIME a 5, 10 or 15 minute session.

See it come apart, part by part · PULSE anatomy →

02 · PROGRAMMABLE

Change the protocol in seconds.

Switching protocols means loading a different program, not re-cabling a rig. These are the families in the library right now.

Carrier

1MHz

US PRO 2000 transducer

Output

0.08–1.6W/cm²

stepped · L / M / H

Session

5 · 10 · 15min

set on the device · timed

Duty cycle

5–100%

across programs

Single-frequency programs

34 · 20 Hz–9.63 kHz

One pulse rate each. 33 of them are included with every account.

20 Hz25 Hz39 Hz40 Hz60 Hz80 Hz90 Hz100 Hz150 Hz200 Hz300 Hz400 Hz432 Hz500 Hz528 Hz800 Hz852 Hz963 Hz1 kHz1.024 kHz1.2 kHz1.5 kHz1.74 kHz2.048 kHz2.852 kHz3.96 kHz4.096 kHz4.32 kHz4.444 kHz5.28 kHz6.39 kHz7.41 kHz8.52 kHz9.63 kHz

Burst programs

2 · 1 Hz–5 Hz

A slow burst rate, each burst a train of pulses at about 1 kHz.

Two-frequency programs

3

One frequency nested inside another.

Your study needs a program that isn’t here?We build it with you.

03 · REPEATABLE

The same program, every session.

Checked on the way in.

A program is written to flash and checked against keys provisioned by UltraDAO. A bad signature never lands.

Read back after.

After each load the app reads the program back from the device and only then says Installed and verified.

Timed on the device.

Sessions are set on the device itself (5, 10 or 15 minutes) and counted down on its lights.

04 · COMPARED

A handheld, not a rig.

Programmable pulsed ultrasound usually means a research system costing $10,000 or more, or a signal chain built on a bench. In many cases, PULSE matches them in one hand.

	Research system or bench rig	PULSE
What it costs	Often $10,000 or more, or a signal generator, an RF power amplifier and a matched transducer bought separately	The US PRO 2000 with PULSE installed, $299 · research packages are built with you
Changing the protocol	Re-set the generator by hand	Load another program from your phone, in seconds
Where it works	On the bench, cabled together	Handheld, on its own power cable
Checking the program	By hand	Every load signature-checked and read back from the device
Programs	Anything the instruments can produce	The signed library, on a 1 MHz carrier

05 · SMALL ANIMALS

Working with mice.

Mind the size of the face.

The transducer face is 24 mm across, wider than a mouse’s head, so a session covers a broad area rather than one structure. Plan positioning and coupling with that in mind.

Your approvals.

Animal work is subject to your institution’s animal-care approvals (IACUC or equivalent). PULSE is sold for research and development use only; it is not a medical device and not FDA cleared.

Bring us the study.

Tell us what you are planning, and we work out the program and the setup with you as part of your research package.

06 · BUILT WITH YOU

Research packages are custom.

A study is more than a device. We scope each research package with you: the programs your protocol needs, the hardware, and the support to run it.

Your idea.

What you want to study, and the questions you want answered.

Your programs.

We build and sign the pulse programs your protocol calls for, alongside the library.

Your package.

Hardware, programs and support, put together for your study and quoted for it.

PULSE · FOR RESEARCH

Bring us your research idea.

Email us what you want to study and the questions you have. We will come back with a research package built around it.

Inquire →See the hardware

Programmableultrasound,in one hand.